Research
Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit/Stress Surfeit Disorder - PubMed
George F. Koob
This research examines how alcohol addiction shifts from seeking pleasure to avoiding the pain of withdrawal, driven by significant changes in the brain's stress and reward circuits.
Alcohol Use DisorderneurobiologyNegative ReinforcementAmygdalaStress SystemsReward DeficitHyperkatifeiaCorticotropin-Releasing Factor
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