The economy of brain network organization

This review examines the organizational principles of brain networks, focusing on the trade-off between physical cost and functional efficiency. It posits that brain architecture is shaped by an economic imperative to minimize wiring and metabolic expenses while maximizing the capacity for complex information processing. By analyzing structural and functional connectivity through graph theory, the authors highlight how features like modularity and highly connected hubs emerge from these competing pressures. Ultimately, the paper suggests that brain disorders can be understood as disruptions to this delicate economic balance of network topology.